![]() ![]() The science is still far from settled, though researchers are keen to find out more. ![]() But semaglutide could one day be more widely useful, as this class of drug may alter the brain’s fundamental reward circuitry. Treatments available today tend to be specific: methadone for opioids, bupropion for smoking. Semaglutide and its chemical relatives seem to work, at least in animals, against an unusually broad array of addictive drugs, says Christian Hendershot, a psychiatrist at the University of North Carolina at Chapel Hill School of Medicine. For years now, scientists have been testing whether drugs similar to semaglutide can curb the use of alcohol, cocaine, nicotine, and opioids in lab animals-to promising results. And the spate of anecdotes might really be onto something. Not everyone on the drug experiences these positive effects, to be clear, but enough that addiction researchers are paying attention. They have reported losing interest in a whole range of addictive and compulsive behaviors: drinking, smoking, shopping, biting nails, picking at skin. It was like a switch had flipped in her brain.Īs semaglutide has skyrocketed in popularity, patients have been sharing curious effects that go beyond just appetite suppression. For the first time-perhaps the first time in her whole life-all of her cravings and impulses were gone. The desire to drink, extinguished once, did not rush in as a replacement either. ![]() But most surprisingly, she walked out of Target one day and realized her cart contained only the four things she came to buy. (Colloquially, it is often referred to as Ozempic, though that is technically just the brand name for semaglutide that is marketed for diabetes treatment.) Her food thoughts quieted down. When she ran errands at Target, she would impulsively throw extra things-candles, makeup, skin-care products-into her cart.Įarlier this year, she began taking semaglutide, also known as Wegovy, after being prescribed the drug for weight loss. “I couldn’t stop from going to that extreme,” she told me. She would spend $500 on organic groceries, only to have them go bad in her fridge. After she got sober in her early 30s, she replaced drinking with food and shopping, which she thought about constantly. Sign up for it here.Īll her life, Victoria Rutledge thought of herself as someone with an addictive personality. At each stop, we’d order enough for at least one taco per person, and we’d sample unique or specialty offerings where possible.This article was featured in One Story to Read Today, a newsletter in which our editors recommend a single must-read from The Atlantic, Monday through Friday. Calls were placed in advance to each location to ensure they were open and able to accommodate large groups. Just like the Pizza Crawl, we also collected $20 up front for the cost of tacos and some drinks, while everyone was responsible for their own alcohol and additional orders. Instead, we went by bike, car and even bus between long distances, while walking between stops two through four. Originally, we considered renting a bus or trolley. Logistics – With Crawl stops in University City, South Philadelphia, Fairmount and Olde Kensington, walking would be impractical.Not making the cut but meriting consideration were spots such as El Vez, Distrito, Loco Pez, Taqueria La Veracruzana and Taco Loco. They also provide a good mix of “Americanized” and “authentic,” casual and more formal, BYO and bar establishments. All have received recognition as being among the best places in town to get tacos. Specific stops – Honest Tom’s Taco Shop, Cantina Los Caballitos, Taqueria Los Taquitos de Puebla, Restaurant Taqueria El Jarocho, La Calaca Feliz, Taco Riendo.Objective – Follow up on the Pizza Crawl and experience the great tacos the city has to offer.Basics – Sample six of the best Philadelphia taquerias on a Saturday in July.The Philadelphia Taco Crawl of July 2013 sought to sample some of the best taco spots in different neighborhoods. In fact, there are fantastic taquerias to be found all throughout the city. Some of the best known Mexican establishments in town are the Stephen Starr and Jose Garces restaurants in Center City and University City, but many of the true gems are the “authentic” South Philly spots that are, regrettably, largely unknown to the average Philadelphian. The taco scene in Philly is diverse and spread out. Cheesesteaks and pizza were already done. On the heels of the highly successful Philadelphia Pizza Crawl of December 2012, it was time to plan another food crawl. ![]()
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